26 January, 2012
Volume 73, Issue 2
X
Volume 73, Issue 2
On the cover: Amir-Zilberstein et al. (pages 279–291) show that adaptation to stressful challenges in zebrafish is modulated by the transcription factor Otp and activity-dependent alternative splicing of the neuropeptide receptor PAC1, which mediates both activation and termination of the stress response. The cover image illustrates a zebrafish in a stressful situation, which causes it to shed its stripes. One of these stripes has been transformed into a schematic depiction of the alternatively spliced exons of the PAC1 gene. Graphic design by Genia Brodsky and Gil Levkowitz, modified with permission from shutterstock.com.
The Cell Podcast
Neuron Connects
Meet the Editors at upcoming meetings.
Joint Keystone Symposia ApoE, Alzheimer's, and Lipoprotein Biology
and Clinical and Molecular Biology of Acute and Chronic Traumatic Encephalaopathies
Feb 26-Mar 2, Keystone CO
Editor: Feyza Sancar
Visit the Cell Press Conference Calendar for more on editorial travel and to update your own conference travel plans.
Most Read Papers
These are the most read papers by download from the Neuron website.
Stay Connected |
 
|
Cell Press Neuroscience Newsletter
Landmarks in Neuroscience
Scientific Voices: What Are the Next Big Questions?
Special Issues on Neuropsychiatric Disease
Free Reviews and neuroscience-related content from across Cell Press
Sign up now! Receive the latest neuroscience news and information, conveniently delivered to your inbox every month.
Featured Job
Faculty Position in Biological Signal Transduction
Department of Molecular and Cellular Physiology
The Department of Molecular and Cellular Physiology at Stanford University School of Medicine seeks to fill a full-time, tenure-track position at the ASSISTANT or ASSOCIATE PROFESSOR rank for studies of biological signaling at the molecular, cellular, tissue, and systems levels. Research areas of special interest include receptors, channels and transporters; cell, tissue and neural circuit assembly and function; intra- and intercellular communication; and computational approaches to link function across organizational levels from molecules to whole organisms. Click for more information.
Job Seekers:
View the latest Jobs in Life Science on the all-new Cell Career Network!
Employers/Recruiters: Post your vacancies and learn more about our various recruitment advertising solutions. Click here for more information.
Publishing with Cell Press
CURRENT ISSUE
|
Featured Article | Dopamine-Ghrelin Crosstalk in Anorexia Kern et al. find that dopamine receptor subtype-2 (DRD2): ghrelin receptor (GHSR1a) heterodimers in hypothalamic neurons allosterically modify canonical DRD2 dopamine signaling and regulate anorexia. Preview by Salahpour and Caron. FREE |
|
Featured Review | AIS Signal Processing Kole and Stuart review recent data on the physiology of the axon initial segment (AIS), suggesting that it represents a dynamic signal processing unit within neurons. FREE |
|
Featured Perspective | Stress and Migraine In this Perspective, Borsook et al. suggest that migraine may be best understood as a disease mediated by runaway stress responses. FREE |
SPOTLIGHT ON
|
NeuroResource | Neuropeptides Become Photoactive Banghart and Sabatini develop two photoactivatable opioid peptides, demonstrating their utility by assessing the spatiotemporal dynamics of opioid signaling. |
|
|
Disease | Regulating Stress through Splicing Amir-Zilberstein et al. identify a biochemical pathway involving the hypothalamic transcription factor OTP that modulates neuronal adaptation to stress via a transcription and alternative splicing cascade. |
|
|
Systems | Endocannabinoid Regulation of DA Reward Seeking Oleson et al. manipulate endocannabinoid neurotransmission in the VTA and show alterations in cue-evoked NAc dopamine levels and reward seeking behaviors. |
|
FEATURED TOPIC: NEUROPSYCHIATRIC DISORDERS
Neuron Articles
|
One in four individuals will have a mental disorder at some point in life and ~10% of the population suffers from a mental disorder at any one time. Advances in neuroscience have significantly furthered knowledge of the etiology and treatment of mental illness. This month, coordinated special issues in Trends in Neurosciences and Trends in Cognitive Sciences jointly address our current understanding of the biological basis of neuropsychiatric disorders and efforts to develop effective treatments. In addition, we present a FREE selection of recent reviews and articles on neuropsychiatric disorders. For more Neuron reviews on this and related topics, please visit our Collections. |
Neuron Articles
Interaction between FEZ1 and DISC1 in Regulation of Neuronal Development and Risk for Schizophrenia
Common DISC1 Polymorphisms Disrupt Wnt/GSK3 Signaling and Brain Development
The Neuronal Transporter GeneSLC6A15Confers Risk to Major Depression
Fear-Conditioning Mechanisms Associated with Trait Vulnerability to Anxiety in Humans
The Genetics of Child Psychiatric Disorders: Focus on Autism and Tourette Syndrome
RECENT REVIEW ISSUES
Neuron publishes special topic-based Review series several times each year, and below are the most recent series. To see all past special issues, click here.
|
Stem Cells |
|
Addiction |
|
Neurogenetics |
|
Child Brain Development |
|
Neural-Immune Interactions |
|
Social Neuroscience |
COLLECTIONS
Neuron has an established history of high impact and insightful review articles and issues and has also been a leading force in the community to feature technological advances, with our Neurotechniques, and their expert explanation, with our Primers. Now we collect together in one online archive the best of Neurons review material.
|
Reviews |
|
Primers |
|
Special Issues |
|
Neurotechniques |
